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Vismodegib

Inh 879085-55-9 Vismodegib; 879085-55-9; GDC-0449; Erivedge; 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691

Catalog No. ABIN5696254

Quick Overview for Vismodegib (ABIN5696254)

Application

Inhibition (Inh)

Chemical Name

Vismodegib; 879085-55-9; GDC-0449; Erivedge; 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691

Purpose

Hedgehog inhibitor

Purity

>98 % (HPLC), NMR (Conforms)

Formula

C19H14Cl2N2O3S

Solubility

May be dissolved in DMSO (200 mg/ml); or ethanol (10 mg/ml, warm)
Geldanamycin
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

Radicicol
Inh 12772-57-5

Geldanamycin- FITC
Inh 30562-34-6 (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate

5-Azacytidine
Inh Cell-permeable 320-67-2 4-Amino-1-ß-D-ribofuranosyl-1,3,5-triazin-2(1H)-one

Nicotinamide
Inh 98-92-0 Pyridine-3-carboxylic acid amide

SAHA (Vorinostat)
Inh Cell-permeable 149647-78-9 Suberoylanilide-hydroxamic acid

Phenylbutyrate Na
Inh 1716-12-7 4-Phenylbutyric acid, sodium salt

CI-994
Inh 112522-64-2 4-(Acetylamino)-N-(2-aminophenyl)benzamide

Tranylcypromine hemisulfate (±)
Inh Cell-permeable 13492-01-8 Trans (±)-2-phenylcyclopropanamine, hemisulfate salt

Tenovin-1
Inh 380315-80-0 N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide

Comment

Source: Synthetic.
Appearance: Off-white powder

Restrictions

For Research Use only
Format

Powder

Handling Advice

GHS Classification: GHS08 health hazard Repr. 2 H361 Suspected of damaging fertility or the unborn child. STOT RE 2 H373 May cause damage to organs through prolonged or repeated exposure. Signal word: Warning Hazard statements: H361 Suspected of damaging fertility or the unborn child. H373 May cause damage to organs through prolonged or repeated exposure. Precautionary statements: P260 Do not breathe dust/fume/gas/mist/vapours/spray. P280 Wear protective gloves/protective clothing/eye protection/face protection. P308+P313 IF exposed or concerned: Get medical advice/attention. P314 Get medical advice/attention if you feel unwell. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations.

Storage

-20 °C
Molecular Weight

421.3

CAS-No

879085-55-9

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